Mouse

Left Button Move the cursor to the square clicked on
Ctrl+Left Button Select more squares without loosing current selection
Double Left Button
On a square
clicked on a line

Insert default block in square
Insert a bar
Alt+ Double Left Insert the alternate block type (Clue Square or Block)
Right Button
On a letter square
On a block square
On a clue square
On a picture
AutoFind words to fit in slot clicked on
Show the square properties
Edit the clue square
Show the picture's properties
Alt+Right button On a letter square: AutoFind words to fit in the word slot in the opposite direction.
Ctrl+Right button On a letter square: Find Word to fit in word slot

The default block type is set in the Advanced page of the Grid Properties dialog box. It can either be a normal block or a clue square, in which case the alternate block type is the other one.

You can also disallow double left-clicks from making bars or blocks in the Grid Properties dialog box. This is sometimes useful as it can be hard work aiming exactly at a narrow line!

See Keyboard for keyboard shortcuts, and the Toolbar topic.